Disadvantages are the hazard if a drug is given too quickly, as plasma concentration may rise at such a rate that normal mechanisms of distribution and elimination are outpaced. The rate of absorption can vary markedly, depending on the physical characteristics of the drug lipid soluble and skin at the site of application. The key features of various routes are discussed here see table 21. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Learn the differences, pros, cons, and considerations for each. Routes of drug administration objectives describe the pharmacokinetic implications of various routes of administration understand the advantages and disadvantage of various routes of administration from a pk point of view routes of administration enteral to do with gastrointestinal gi tract e. For a more detailed description of the specific methodology involved in drug administration, the references at the end of this chapter include several excellent resources on this topic. Other routes of administration are required when the oral route cannot be used, for example. Slow absorption and action can not used in emergency irritable and unpalatable drugs. Issues of particular importance in the care of pediatric patients, especially factors that could lead to drugrelated toxicity or adverse responses, are emphasized. Routes of drug administration advantages of inhalation rapid action of the drug, with local effects with in the respiratory tract potent drugs may be given in small. For many advantages, orally taken medications are much preferred than those of other routes. The advantages of topical antibiotics include the following 55, 63. It may be in the form of tablets, capsules, syrup, emulsions or powders.
Comments off on routes of drug administration ppt pdf 10 routes of drug administration routes of drug administration. Discuss the role of safety, accuracy, and attitude in risk prevention associated with parenteral preparation. Oral route has a slow onset of action, hence not used in. Routes of administration worksheet accommodations for learning differences for reinforcement, the student will design a comparative chart listing dosage forms, their appropriate route of administration, advantages and. Give one example of drug administrated via each route given and the rationale for choosing the example route. The administration is mostly done by using needle and is of following types. This route is where a medicament is applied on to skin to produce its effects. Discuss the advantages of a transdermal dosage form. The intrathecal route allows direct drug administration to the csf by circumventing the bloodbrain barrier. There are various routes of administration, each of which has associated advantages and disadvantages. Jan 21, 2019 you will get here advantages and disadvantages of routes of drug administration. Intrathecal route of drug delivery can save lives or improve. Safe convenient self administered, pain free, noninvasive and easy to take economical compared to other parenteral routes usually good absorption takes place along the whole length of the gi tract no need for sterilization disadvantages. Advantages and disadvantages of parenteral administration.
Monica may lopez september 06, 2016 common routes of drug administration route bioavailability advantages disadvantages drugs. Routes of administration there are many ways that the drug can be administrated to the body for treatment of diseases. Advantages and disadvantages of different routes of. These changes have often resulted in improved patient adherence to. This method also provides the most difficult pathway for the drug to reach the targeted area. Jun 17, 2014 in this video lecture, professor fink identifies the major routes of administration of drugs and discusses the advantages and disadvantages of each. This route is risky but has many advantages than the oral route of drug administration. Routes of administration of a drug are determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. In this video lecture, professor fink identifies the major routes of administration of drugs and discusses the advantages and disadvantages of each. What are the advantages and disadvantages of topical. Disadvantages not suitable for emergency as onset of action of orally administered drugs is slow. Such immediacy results in rapid acquisition and strong maintenance of behavior.
Intravenous therapy in healthcare advantages, complications, applications and latest news when substances i. Transdermal and topical drug administration in the treatment. In this method of administration, drug is applied on to skin or other body surfaces. There are various routes of administration box 1, each of which has advantages and disadvantages. Routes of administration an overview sciencedirect topics. A free powerpoint ppt presentation displayed as a flash slide show on id. Dosage form design may also be used modify the rate of absorption. Discuss united states pharmacopeia chapters applicable to. This route of administration is possible if the drug is in liquid dosage form. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience.
Oral route is the most common route of drug administration. The oral route of administration is the safest, most economical and the most convenient way of giving medicines. That is the drug acts only at the site of application and. Topically and transdermally administered opioids are characterised by a lower risk of addiction compared to oral and parenteral routes. A scheme of the different sites for parenteral drug administration is presented in figure 6. The route is suitable for administration of drugs that are not absorbed from the gut or are too irritant anticancer agents to be given by other routes. Purchase routes of drug administration 1st edition. Factors to be considered when choosing certain route. Each route has specific purposes, advantages, and disadvantages.
Higher concentration of the antibiotic when applied to the. The drug may be swallowed, allowing oral delivery, or it may be placed under the tongue sublingual or between the gums and cheek buccal, facilitating direct absorption into the bloodstream. Each route has several variations, and each offers distinct advantages and disadvantages. The transdermal route apart from the abovementioned advantages and provision of long period of analgesia may be more convenient, especially for patients who are unable to take drugs orally. These advantages include safety, good patient compliance, ease of ingestion, pain avoidance, and versatility to accommodate various types of drugs sastry et al. Administration of drugs by injection, by topical application to skin or by inhalation through the lungs are all parenteral. Describe advantages and disadvantages of the parenteral route of administration. About sublingual and buccal medication administration. Parenteral drug administration their types, advantages and.
You will get here advantages and disadvantages of routes of drug administration. This article deals with the salient features, advantages and disadvantages of some of the alternative routes of drug administration transdermal, pulmonary and parenteral routes. Low risk of systemic adverse events and drug interactions. Alternative routes of drug administration transdermal. Other disadvantages with parenteral routes are patient discomfort, the need for sterile.
All the routes of drug administration need to be understood in terms of their implications for the effectiveness of the drug therapy and the patients experience of drug treatment. Sublingual and buccal medication administration are ways to take certain oral drugs. Oral route advantages safer cheaper painless convenient for repeated and prolonged use. A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of drug administration intravenous iv drugs may be given into a peripheral vein over 1 to 2 minutes or longer by infusion. Different routes are oral route, sublingual route, rectal route, parentral routes, subcutaneous, intravenous, intramuscular. Controlled laboratory and clinical trials are vital to determine the safe use of medications originally formulated to be administered by other routes. Start studying advantages and disadvantages of different routes of administration. Routes of administration are generally classified by the location at which the substance is applied. Routes other than enteral are called parenteral routes of administration. The mouth route is the most commonly used route of drug administration due to the ease in which the drugs can be taken.
As its the simplest and easiest way for any patient to take a medication. Oral drug administration an overview sciencedirect topics. Sc administrat ion of drugs consists in injecting them under the skin into the adipose layer. Selecting a right route of drug administration by a physician improves patients health. Intravenous therapy advantages, complications and applications. Routes of drug administration play a major role in a medical treatment. Absorption after oral administration can be quite variable. Common examples include oral and intravenous administration.
The main role of any route is to deliver the drug to the target part of the body so it can give its therapeutic effect. Aerosols localtopical route of drug administration in this route the drug is applied on the skin. Advantages and disadvantages of routes of drug administration. Ppt routes of drug administration powerpoint presentation. Most drugs can be administered by a variety of routes. Some advantages of administering drugs through the oral mucosa are. Rapid injections are used to treat epileptic seizures, acute asthma, or cardiac arrhythmias. This statement focuses on the advantages and disadvantages of alternative routes of drug administration. Intravenous route an overview sciencedirect topics. This essay includes the brief description and discussion of the advantages and disadvantages of major routes of drug administration. Oral dosage forms advantages, disadvantages, and classification. Appropriate for any patient, whatever the age is the most natural and easiest route of administration. Aug 15, 20 there are various routes of administration, each of which has associated advantages and disadvantages.
Routes of drug administration oral po oral administration will be covered in more detail in subsequent chapters. Pdf common routes of drug administration monica may lopez. Explain the correct techniques for administration of eye drops, metereddose. Drug administration drugs merck manuals consumer version. Most risky route vital organs like heart, brain etc get exposed to high concentrations of the drug. Administering a drug through the iv route involves the introduction of a drug solution through a needle, directly into a vein. Routes of drug administration for mbbs 1st year dr. American academy of pediatrics alternative routes of. Routes of administration other than enteral route are called parenteral routes. Oral route oral refers to two methods of administration. Drug is delivered immediately upon the completion of a response requirement and since delivery is into a vein, there is a rapid onset of drug effects. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. Enteral administration administering a drug by mouth safest and most common, convenient, and economical method of drug.
Pdf systemic absorption of a drug depends on its physicochemical properties, the nature of the. This route is one of the safest route as the drug cannot product poisonous effects. Drug administration drugs msd manual consumer version. A list of commonly used routes of drug administration can be found below, along with useful information about dosage and abbreviations. Mar 17, 2018 the transdermal route apart from the abovementioned advantages and provision of long period of analgesia may be more convenient, especially for patients who are unable to take drugs orally. Our understanding of drug transport across tissues has increased. What are the advantages and disadvantages of oral route drug. Administration via this route is less desirable for drugs that are irritating to the gi tract or when the.
Discuss united states pharmacopeia chapters applicable to phar. Explain the major routes of administration and the advantages and disadvantages associated with each route of administration. The route of administration is the way through which the dosage form is. Routes of administration worksheet accommodations for learning differences for reinforcement, the student will design a comparative chart listing dosage forms, their appropriate route of administration, advantages and disadvantages of each, and examples of drugs for each. Introduction a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body. During the past 20 years, advances in drug formulations and innovative routes of administration have been made.
Routes of administration factors to be considered when. This route of administration achieves systemic effects by application of drugs to the skin, usually via a transdermal medicated adhesive patch. The dose of the drug required is smallest bioavailability is 100% and even large volumes can be infused. New routes of drug administration offer many advantages for the care of pediatric patients. There are various routes of administration available, each of which has associated advantages and disadvantages. Alternative routes of drug administrationadvantages and.
These routes need to be understood in terms of their implications for the effectiveness of the drug therapy and the patients experience. Issues of particular importance in the care of pediatric patients, especially factors that could lead to drug related toxicity or adverse responses, are emphasized. Advantages and disadvantages of thetopical route local therapeutic effects. American academy of pediatrics alternative routes of drug.1475 399 1540 491 1251 349 86 140 739 1118 60 101 1473 1136 292 162 139 1585 734 394 416 469 473 541 243 1556 1191 1298 281 235 740 521 1105 643 403 54 1445